posters

BIO MARKERS AND CELL BIOLOGY

BIO MARKERS


Exploring the Cell Biology of Gene-Environment Interactions in ALS with Human iPSCs              

Dr Bryony Thorne

Serum Neurofilament Light as a Prognostic Biomarker in ALS

Dr Jayden Clark


Neutrophil-to-lymphocyte ratio as a biomarker for progression of amyotrophic lateral sclerosis             

Dr Robert Nona


Tracking Cortical Plasticity in MND Patients using 7T MRI       

Dr Thomas Shaw


Biomarkers of Immune Dysfunction for Motor Neuron Disease            

Vassilios Karnaros


Identifying the role of gut microbiome in ALS using zebrafish disease model  

Dr Pradeep Manuneedhi Cholan



CELL BIOLOGY


RNA-interactions alter the nanoscale dynamics of pathogenic MND-linked TDP-43 mutations.

Dr Adekunle Bademosi


In vivo axonal transport of diverse organelles in MND              

Dr Andrew Tosolini


Phosphorylation alters TDP-43 protein-protein interactions. 

Elise Kellett


Using iPSC-Derived Organoids to investigate Oligodendrocyte Involvement in Motor Neuron Disease  

Francois-Xavier Beau


Phosphorylated TDP-43 shows mislocalisation and more dynamic nuclear biomolecular condensates in an in vivo zebrafish model.

Grant Richter


The effect of molecular chaperones on TDP-43 aggregation via liquid-liquid phase separation
Joshua Trowbridge

Calcium permeability of AMPA receptors is influenced by estrogen in a mouse model of ALS-associated TDP-43 pathology.
Laura Reale

Characterising cortical interneurons in a novel mouse model of amyotrophic lateral sclerosis driven by cortical hyperexcitability
Dr Mouna Haidar

A loss of Neuromuscular Maintenance in MND.
A/Prof Peter Noakes

Modelling DCTN1 deficiency to study neurodegenerative cascades in MND.
Pippa Pringuer

A molecular platform for the rapid functional study of oligogenic MND candidate genes in vitro
Sharlynn Wu

Assessing the role of CHCHD10 in MND
Dr Shu Wang

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis.
Taide Wang

Is FUS a pathological prion-like protein in MND?
Vanessa Hollingsworth

Increased levels of UBA1 protect against mutant SOD1 toxicity.
Dr Isabella Lambert-Smith

A human stem-cell derived model of the neuromuscular junction to investigate axonal alterations in ALS.
Dr Rachel Atkinson

HSPB1 mediates cytoplasmic TDP-43 condensation and inhibits aggregation of the TDP-43 low complexity domain. 
Thomas Walker

Do Oligodendrocytes Exhibit Pathology in TDP-43 Related MND?
Katherine Lewis

Ebselen derivatives for treating SOD1 fALS
Victoria Shephard


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